POS1486 RELATIONSHIP BETWEEN THE EULAR/ACR CLASSIFICATION CRITERIA AND ORGAN DAMAGE IN SYSTEMIC LUPUS ERYTHEMATOSUS

Background: Objectives To study the relationship between 2019 EULAR/ACR classification criteria and organ damage in patients with systemic lupus erythematosus (SLE) Methods Patients involved a cross-sectional validation of judged by panel rheumatologists to be clinical SLE were studied. Those who fulfilled at their last clinic visit stratified into 2 groups based on cut-off score 20. The international collaborating (SLICC) index (SDI) was compared these two groups. Relationship among domains SDI all studied Spearman’s rank correlation. Results 562 (93.6% women; age 36.5±14.1 years; follow-up duration 11.6±6.6 years). mean median scores those (N=542) 24.6±7.3 24 (interquartile range 19-30), respectively. A total 392 had ≥20 (group 1) 150 10-19 2). Group 1 significantly higher prevalence fever, alopecia, oral ulcers, acute skin lesions, arthritis, serositis, seizure, hemolytic anemia, leukopenia renal disease, so anti-dsDNA, anti-Sm, antiphospholipid antibodies low complement state. Organ (SDI ≥1) occurred 232 (42.8%) patients. group renal, cardiovascular, dermatological gonadal than 2. neuropsychiatric domain correlated positively SDI. strongest correlation (Rho 0.30; p<0.001). scored 10 points 8 or 4 points. Gonadal also more common 10-point 8-point group. Conclusion In addition disease classification, may have role predicting prognosis. REFERENCES: NIL. Acknowledgements: Disclosure Interests None Declared.